Review

[Oncogene] The authors summarize how genetically-engineered mouse models of SCLC have contributed significantly to our understanding of the disease in the past two decades, as well as recent advances in modeling SCLC in mice that allow investigators to bypass limitations of the previous generation of genetically-engineered mouse models.

[Biomaterials Science] Scientists highlight the progress and impact of the hydrogel-based drug delivery system in IBD treatment through regulation of physical barrier immune responses, promotion of mucosal repair, and improvement of gut microbiota.

[Biofactors] The authors outline and discuss recent progress in our understanding of the role of exosomes in the prostate cancer microenvironment, like their involvement in prostate cancer occurrence, progression, angiogenesis, epithelial–mesenchymal transition, metastasis, and drug resistance.

[Cell Death & Disease] The authors provide an updated understanding of NK cell development, functions, and their applications in disease therapy. They explored the rationale for utilizing engineered NK cell therapies, such as CAR-NK cells, and discuss the differences between CAR-T and CAR-NK cells.

[Cell Regeneration] The authors conduct a comprehensive research to further understand the intertwine between the mechanisms of action of intervertebral disc (IVD) components and the therapeutic potential of MSCs, exploring their characteristics, and how to optimize their use and establish them safely in distinct settings for low back pain treatment.

[mBio] The authors provide an overview of the current knowledge regarding how lncRNAs regulate HIV gene expression, categorizing them as either activators or inhibitors of viral gene expression and infectivity.