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Neoadjuvant Chemotherapy for Early-Stage Colon Cancer

[Cancer Treatment Reviews] The authors conduct a systematic search of the literature, and provide a thorough and in-depth analysis of the findings from randomised clinical trials trials, highlighting the advantages and disadvantages of neoadjuvant chemotherapy for early-stage colon cancer.

Nanotechnology Applications in Breast Cancer Immunotherapy

[Small] Scientists highlight the recent advances in nanoimmunotherapeutic development, with a focus on breast cancer.

Same Yet Different — How Lymph Node Heterogeneity Affects Immune Responses

[Nature Reviews Immunology] Scientists review the structure and function of the lymphatic system and then focus on the factors that lead to functional heterogeneity among different lymph nodes.

The Dual Role of Regulatory T Cells in Hepatitis B Virus Infection and Related Hepatocellular Carcinoma

[Immunology] The authors discuss pertinent studies concerning Tregs in hepatitis B virus (HBV) infection, HBV-related cirrhosis, and HCC. Furthermore, they summarize Treg responses to antiviral therapy and provide Treg-targeted therapies specific to HBV and HCC.

Translating Mesenchymal Stem Cell and Their Exosome Research into GMP Compliant Advanced Therapy Products: Promises, Problems and Prospects

[Medicinal Research Reviews] The authors review the hurdles encountered in translation of MSCs and MSC–exosomes from the research bench to an advanced therapy product compliant with good manufacturing practice.

Mitochondrial-Targeted Antioxidant Attenuates Preeclampsia-Like Phenotypes Induced by Syncytiotrophoblast-Specific Gαq Signaling

[Science Advances] Investigators present data supporting increased Gαq signaling and antioxidant responses within villous and syncytiotrophoblast samples of human preeclamptic placenta.

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