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Crosstalk and Plasticity Driving between Cancer-Associated Fibroblasts and Tumor Microenvironment: Significance of Breast Cancer Metastasis

[Journal of Translational Medicine] Scientists summarize the inhibitory effects of different natural compounds on targeting cancer-associated fibroblasts and the advantages of different drug combinations.

γδ T Cells: Origin and Fate, Subsets, Diseases, and Immunotherapy

[Signal Transduction and Targeted Therapy] The authors elucidate functional differences between γδ T cells and their αβ T cell counterparts and provide an overview of major milestones in γδ T cell research since their discovery in 1984.

Asteroid Impact: The Potential of Astrocytes to Modulate Human Neural Networks within Organoids

[Frontiers In Neuroscience] Scientists summarize the potential capability of using organoids to further understand the mechanistic role of astrocytes upon neural networks, including the production of extracellular matrix components and reactive signaling cues.

Astrocytes and Microglia in the Coordination of CNS Development and Homeostasis

[Journal Of Neurochemistry] Investigators focus on astrocytes and microglia highlighting research that documents either suggestive or established coordinated actions by these glial cells in various CNS processes.

Engineered Synthetic Matrices for Human Intestinal Organoid Culture And Therapeutic Delivery

[Advanced Materials] Human intestinal organoids derived from PSCs or adult stem cell biopsies represent a powerful platform to study human development, drug testing, and disease modeling in vitro, and serve as a cell source for tissue regeneration and therapeutic advances in vivo.

Mitigation of Acute Radiation Syndrome (ARS) with Human Umbilical Cord Blood

[International Journal Of Radiation Biology] Scientists discuss acute radiation syndrom and its sub-syndromes, and to highlight recent findings regarding the use of umbilical cord blood for radiation injury.

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