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vascular endothelial cells

Dispatch and Delivery at the ER – Golgi Interface: How Endothelial Cells Tune Their Hemostatic Response

[FEBS Journal] The authors summarize recent evidence that modulation of the early secretory pathway has great impact on the biogenesis and release of Weibel-Palade bodies.

Nintedanib Ameliorates Oxidized Low-Density Lipoprotein-Induced Inflammation and Cellular Senescence in Vascular Endothelial Cells

[Bioengineered] Scientists found that in oxidized low-density lipoprotein-treated HUVECs, the increased production of total cholesterol, free cholesterol, and pro-inflammatory cytokines were observed, reversed by 10 μM and 25 μM Nintedanib.

Necroptosis Triggers Spatially Restricted Neutrophil-Mediated Vascular Damage during Lung Ischemia Reperfusion Injury

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that TLR4 signaling in vascular endothelial cells and downstream NADPH oxidase 4 expression mediate the arrest of neutrophils, a step upstream of their extravasation.

Autophagy and Skin Wound Healing

[Burns & Trauma] Understanding the relationship between autophagy and skin wound healing may provide novel strategies for the clinical treatment of wound healing.

Bivalent-Histone-Marked Immediate-Early Gene Regulation Is Vital for VEGF-Responsive Angiogenesis

[Cell Reports] Scientists evaluated the global mapping of VEGF-mediated dynamic transcriptional events, focusing on major histone-code profiles using chromatin immunoprecipitation sequencing.

Zhilong Huoxue Tongyu Capsule Alleviated the Pyroptosis of Vascular Endothelial Cells Induced by Ox-LDL through miR-30b-5p/NLRP3

[Evidence-Based Complementary and Alternative Medicine] Human coronary artery endothelial cells were induced with oxidized low-density lipoprotein to obtain cellular atherosclerosis models.

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