vitiligo

[Cancer Cell International] Expression levels of miR-630 can be used as markers for prediction of cancer course. Moreover, miR-630 can influence response to chemoradiotherapy.

[Cell Death Discovery] Researchers found that other cell death modalities may exist in addition to the well-recognized apoptosis and necroptosis in H2O2-treated melanocytes.

[Stem Cells and Development] Researchers discovered that proper micro-injury effectively induced hair regeneration by activating the hair follicle stem cell proliferation and migration downwards to the hair matrix, finally shifting the hair follicle stage from telogen into anagen.

[Nature] The authors identified subsets of dermal fibroblasts that were responsible for driving patterned autoimmune activity, by using a robust mouse model of vitiligo that was based on the activation of endogenous auto-reactive CD8+ T cells that targeted epidermal melanocytes.

[Incyte] Incyte announced the validation of the European Marketing Authorization Application for ruxolitinib cream, a topical JAK inhibitor, as a potential treatment for adolescents and adults with non-segmental vitiligo with facial involvement.

[Immunity] Expanded resident memory populations were present in melanoma-involved lymph nodes from patients, and their transcriptional signature predicted better survival.