Wnt/β-catenin

[Journal of Ethnopharmacology] Researchers evaluated the healing effect of quercetin on cutaneous wound models in vivo and in vitro, and revealed the Wnt/β-catenin pathway and telomerase reverse transcriptase involved mechanisms.

[Clinical and Experimental Pharmacology and Physiology] The authors explored the effect of the upregulation or downregulation of the NPM1 protein on the malignancy of prostate cancer and its possible signaling pathway.

[Cell Death & Disease] Investigators confirmed that ETV4 was significantly upregulated by Hepatitis B virus X protein (HBx) and involved in super-enhancer-associated chromatin accessibility. Increased expression of ETV4 promoted HCC cell invasion and metastasis by upregulating DVL2.

[Cell Death & Disease] Overexpression of RBM5-AS1 facilitated proliferation, migration, invasion, EMT, and stemness maintenance of breast cancer cells in vitro and in vivo.

[Heliyon] Researchers investigated regulatory mechanisms underlying β-catenin coactivator usage in human pancreatic carcinoma PANC-1 cells through combinatorial analysis of chromatin immunoprecipitation-sequencing and RNA-sequencing.

[Cancer Cell International] Ebp1 expression was substantially higher in malignant melanoma (MM) than it was in normal skin, and Ebp1 was linked to the clinical stage and lymph node metastases of patients with MM.