xenograft models

[International Journal of Oncology] Researchers detected the expression of interleukin‑28 receptor α subunit (IL‑28RA) in PDAC tissues using immunofluorescence staining and western blotting.

[Nature Communications] LINC00842 expression was upregulated in pancreatic ductal adenocarcinoma and induced by high concentration of glucose via transcription factor YY1.

[Oncogene] Investigators showed the differentially expressed miRNAs in oxaliplatin-sensitive and oxaliplatin-resistant colorectal cancer cells through miRNA microarray technology and found that miR-135b-5p was significantly increased in oxaliplatin-resistant cells.

[Cell Death & Disease] Researchers selected highly expressed microRNAs with different read counts as candidate microRNAs and then tested whether the microRNAs were differentially expressed in hepatocellular carcinoma (HCC) tumour tissues, and they found that their expression was related to the HCC prognosis.

[Oncogene] Reserachers found that high Yes-associated protein (YAP) expression is associated with poor prognosis in malignant glioma patients undergoing radiotherapy.

[Molecular Therapy-Nucleic Acids] The effects of conditioned medium collected from dedifferentiated adipocytes on pancreatic cancer cell proliferation, motility, metastasis and epithelial-mesenchymal transition (EMT) were evaluated by western blot analysis, colony forming, real-time cell analysis, 5-ethynyl-2’-deoxyuridine, immunofluorescence, Transwell and wound healing assays in vitro.