UBE2T Promotes Radiation Resistance in Non-Small Cell Lung Cancer via Inducing Epithelial-Mesenchymal Transition and the Ubiquitination-Mediated FOXO1 Degradation

Using bioinformatic analyses, researchers found that UBE2T was associated with survival, tumor size, lymph node metastasis and distant metastasis. They used colony formation, EdU incorporation, scratch, transwell assays, flow cytometry, immunofluorescence and western blot to assess the role of UBE2T in vitro and in vivo.