NPRL3 Loss Alters Neuronal Morphology, mTOR Localization, Cortical Lamination, and Seizure Threshold

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To model human malformations of cortical development associated with nitrogen permease regulator-like 3 (NPRL3) variants, researchers created a focal Nprl3 KO in fetal mouse cortex by in utero electroporation and found altered cortical lamination and white matter heterotopic neurons
[Brain]
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