FC Galactosylation of Anti-platelet hIgG1 Alloantibodies Enhance Complement Activation on Platelets

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Scientists found IgG Fc glycosylation of anti-HLA antibodies to be highly variable between patients with platelet refractoriness, especially with respect to galactosylation and sialylation of the Fc-bound sugar moiety.
[Haematologica]
Abstract