PD-1 Cooperates with AIRE-Mediated Tolerance to Prevent Lethal Autoimmune Disease

By
Justin.choi
-
0
215
Using a range of mouse genetic models, researchers uncovered a critical tolerogenic axis between the autoimmune regulator, AIRE, and the immune checkpoint molecule, PD-1.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract