TY - JOUR TI - Dental follicle stem cells rescue the regenerative capacity of inflamed rat dental pulp through a paracrine pathway AU - Hong, Hong AU - Chen, Xiaochuan AU - Li, Kun AU - Wang, Nan AU - Li, Mengjie AU - Yang, Bo AU - Yu, Xiaoqi AU - Wei, Xi T2 - Stem Cell Research & Therapy AB - Pulpitis is a common dental disease characterized by sustained inflammation and impaired pulp self-repair. Mesenchymal stem cell-based minimally invasive vital pulp therapy (MSC-miVPT) is a potential treatment method, but its application is limited by the difficulty in acquiring MSCs. We recently revealed the immunomodulatory effects of rat dental follicle stem cells (rDFSCs) on acute lung injury. The present study focused on the paracrine effects of rDFSCs on the inflammation and regeneration of rat injured dental pulp to detect whether DFSCs are a potential candidate for MSC-miVPT. DA - 2020/08/03/ PY - 2020 DO - 10.1186/s13287-020-01841-1 DP - BioMed Central VL - 11 IS - 1 SP - 333 J2 - Stem Cell Research & Therapy SN - 1757-6512 UR - https://doi.org/10.1186/s13287-020-01841-1 Y2 - 2020/08/05/19:23:53 ER -