TY - JOUR TI - Investigating cellular and molecular mechanisms of neurogenesis in Capitella teleta sheds light on the ancestor of Annelida AU - Sur, A. AU - Renfro, A. AU - Bergmann, P. J. AU - Meyer, N. P. T2 - BMC Evolutionary Biology AB - Diverse architectures of nervous systems (NSs) such as a plexus in cnidarians or a more centralized nervous system (CNS) in insects and vertebrates are present across Metazoa, but it is unclear what selection pressures drove evolution and diversification of NSs. One underlying aspect of this diversity lies in the cellular and molecular mechanisms driving neurogenesis, i.e. generation of neurons from neural precursor cells (NPCs). In cnidarians, vertebrates, and arthropods, homologs of SoxB and bHLH proneural genes control different steps of neurogenesis, suggesting that some neurogenic mechanisms may be conserved. However, data are lacking for spiralian taxa. DA - 2020/07/14/ PY - 2020 DO - 10.1186/s12862-020-01636-1 DP - BioMed Central VL - 20 IS - 1 SP - 84 J2 - BMC Evolutionary Biology SN - 1471-2148 UR - https://doi.org/10.1186/s12862-020-01636-1 Y2 - 2020/07/15/21:01:54 ER -