NewslettersImmune Regulation News The Immune Checkpoint B7x Expands Tumor-Infiltrating Tregs and Promotes Resistance to Anti-CTLA-4 Therapy By Danielle Corrigan - May 6, 2022 0 The authors showed that transduction and stable expression of B7x in multiple syngeneic tumor models led to the expansion of immunosuppressive regulatory T cells (Tregs). [Nature Communications] Full Article