NewslettersNeural Cell News Neuronal NLRP3 Is a Parkin Substrate That Drives Neurodegeneration in Parkinson’s Disease By Bob - June 1, 2022 0 Researchers showed that loss of parkin activity in mouse and human dopamine (DA) neurons results in spontaneous neuronal NOD-like receptor protein 3 (NLRP3) inflammasome assembly, leading to DA neuron death. [Neuron] AbstractGraphical Abstract