NewslettersDermal Cell News UVB-Induced SFRP1 Methylation Potentiates Skin Damage by Promoting Cell Apoptosis and DNA Damage By mladbrook - June 6, 2022 0 Researchers found a significant downregulation of secreted frizzled-related protein 1 (SFRP1) in HaCaT, A431, and SCL-1 cells after ultraviolet radiation B (UVB) irradiation. [Experimental Dermatology] Abstract