NewslettersEndothelial Cell News The Onset of PI3K-Related Vascular Malformations Occurs during Angiogenesis and Is Prevented by the AKT Inhibitor Miransertib By Danielle Corrigan - June 13, 2022 0 Researchers demonstrated that the Pik3caH1047R activating mutation in endothelial cells triggered a transcriptome rewiring that led to enhanced cell proliferation. [EMBO Molecular Medicine] Full ArticleGraphical Abstract