Scientists showed that the clinically approved compound ursodeoxycholic acid, by degrading TGF-β, enhanced antitumor immunity through restraining Treg cell differentiation and activation in tumor-bearing mice.
[Nature Communications]
Home Newsletters Immune Regulation News Ursodeoxycholic Acid Reduces Antitumor Immunosuppression by Inducing CHIP-Mediated TGF-β Degradation
