NewslettersESC & iPSC News Hbxip Is Essential for Murine Embryogenesis and Regulates Embryonic Stem Cell Differentiation through Activating mTORC1 By Bob - June 22, 2022 0 The authors demonstrated that homozygous knockout of Hbxip led to embryonic lethality, with retarded growth around E7.5, and that depletion of Hbxip compromised the self-renewal of ESCs. [Development] Abstract