NewslettersHuman Immunology News Genome-Wide CRISPR Screens of T Cell Exhaustion Identify Chromatin Remodeling Factors That Limit T Cell Persistence By Danielle Corrigan - June 24, 2022 0 In vivo CRISPR screens in murine and human tumor models demonstrated that perturbation of the INO80 and BAF chromatin remodeling complexes improved T cell persistence in tumors. [Cancer Cell] AbstractGraphical Abstract