NewslettersNeural Cell News Temozolomide-Induced Guanine Mutations Create Exploitable Vulnerabilities of Guanine-Rich DNA and RNA Regions in Drug-Resistant Gliomas By Bob - June 29, 2022 0 Scientists reported that temozolomide-resistant glioblastoma has guanine (G) mutations that disrupted the G-rich DNA G-quadruplex and splice sites that lead to deregulated alternative splicing. [Science Advances] Full ArticlePress Release