NewslettersIntestinal Cell NewsMesenchymal Cell News PTEN and LKB1 Are Differentially Required in Gli1-Expressing Mesenchymal Cells to Suppress Gastrointestinal Polyposis By Bob - July 26, 2022 0 Investigators revealed that PTEN or LKB1 deficiency in Gli1+ gut mesenchymal cells, but not intestinal epithelium, drove polyp formation histologically resembling polyposis in human patients. [Cell Reports] Full ArticleGraphical Abstract