Both in vitro and in vivo experiments confirmed that SIRT1 played important roles in adiponectin inhibiting the fibrotic phenotype transformation and proliferation of scar fibroblasts and improving skin fibrosis.
[iScience]
Adiponectin Ameliorates Hypertrophic Scar by Inhibiting YAP Transcription through SIRT1-Mediated Deacetylation of C/EBPβ and Histone H3
