NewslettersCancer Stem Cell News Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells Through Lead Optimization By Bob - November 23, 2022 0 In order to develop potent and selective CYP4Z1 inhibitors, a series of novel N-hydroxyphenylformamidines were rationally designed and synthesized from a pan-CYP inhibitor HET0016. [Journal of Medicinal Chemistry] AbstractGraphical Abstract