Short Peptide Domains of the Wnt Inhibitor sFRP4 Target Ovarian Cancer Stem Cells by Neutralizing the Wnt β-Catenin Pathway, Disrupting the Interaction Between β-Catenin and CD24 and Suppressing Autophagy

The authors explored the effectiveness of short micropeptides SC-301 and SC-401 on CSC properties, epithelial-mesenchymal transition, apoptosis, and autophagy in ovarian CSCs enriched from PA-1 and SKOV-3 cell lines.