IGFBP5 Is an ROR1 Ligand Promoting Glioblastoma Invasion via ROR1/HER2-CREB Signaling Axis

Researchers reported Insulin-like Growth Factor-Binding Protein 5 (IGFBP5), a ligand for Receptor tyrosine kinase like Orphan Receptor 1 (ROR1), as a promising target for glioblastoma stem-like cell invasion.