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Versican Promotes T Helper 17 Cytotoxic Inflammation and Impedes Oligodendrocyte Precursor Cell Remyelination

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The authors correlated high versican-V1 expression in multiple sclerosis (MS) lesions with deficient premyelinating oligodendrocytes, and highlighted its selective upregulation amongst chondroitin sulfate proteoglycans members in experimental autoimmune encephalomyelitis lesions modeling MS.
[Nature Communications]
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