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The Healthy Exocrine Pancreas Contains Preproinsulin-Specific CD8 T Cells That Attack Islets in Type 1 Diabetes

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The authors quantified preproinsulin-specific CD8+ T cells within different areas of the human pancreas from nondiabetic controls, autoantibody-positive donors, and donors with type 1 diabetes to investigate their role in diabetes development.
[Science Advances]

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