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Deubiquitylase USP12 Induces Pro-Survival Autophagy and Bortezomib Resistance in Multiple Myeloma by Stabilizing HMGB1

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Researchers identified an important role of the deubiquitylase ubiquitin-specific protease-12 (USP12) in pro-survival autophagy and resultant bortezomib resistance in multiple myeloma by stabilizing high mobility group box-1 (HMGB1).
[Oncogene]

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Abstract
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