NewslettersEndothelial Cell News Aspartate Metabolism in Endothelial Cells Activates the mTORC1 Pathway to Initiate Translation during Angiogenesis By Danielle Corrigan - May 16, 2022 0 The authors showed in both human cell lines and mouse models that during developmental and pathological angiogenesis, endothelial cells used glutaminolysis-derived glutamate to produce aspartate via aspartate aminotransferase. [Developmental Cell] AbstractGraphical Abstract