NewslettersPancreatic Cell News Adaptive Stimulation of Macropinocytosis Overcomes Aspartate Limitation in Cancer Cells Under Hypoxia By Danielle Corrigan - June 21, 2022 0 The authors investigated GOT2-catalysed mitochondrial aspartate synthesis as an essential metabolic dependency for the proliferation of pancreatic tumour cells under hypoxic culture conditions. [Nature Metabolism] Full Article