NewslettersESC & iPSC News KCNQ1-Deficient and KCNQ1-Mutant Human Embryonic Stem Cell-Derived Cardiomyocytes for Modeling QT Prolongation By Bob - June 29, 2022 0 KCNQ1 was knocked out in hESC H9 line using the CRISPR/cas9 system. KCNQ1-deficient and KCNQ1-mutant hESCs were differentiated into cardiomyocytes through a chemically defined differentiation protocol. [Stem Cell Research & Therapy] Full Article