NewslettersOrganoid News KS10076, a Chelator for Redox-Active Metal Ions, Induces ROS-Mediated STAT3 Degradation in Autophagic Cell Death and Eliminates ALDH1+ Stem Cells By lbeveridge - July 19, 2022 0 Patient-derived organoid models demonstrated that KS10076 efficiently represses cancer cells with active KRAS, and fluorouracil resistance, which suggested clinical advantages. [Cell Reports] Abstract