Nucleosome Remodeling and Deacetylation Complex and MBD3 Influence Mouse Embryonic Stem Cell Naïve Pluripotency under Inhibition of Protein Kinase C

Investigators found that, compared with 2iL-derived mES, protein kinase C-derived mES showed low mRNA expression of NuRD complex subunits, including MBD3, HDAC1/HDAC2, MTA1, and RbAP46/RbAP48.