NewslettersESC & iPSC News Engineering an Adenine Base Editor in Human Embryonic Stem Cells with Minimal DNA and RNA Off-Target Activities By Bob - August 3, 2022 0 Scientists tested different combinations of off-target reduction methods to further diminish off-target effects of adenine base editors without compromising their on-target editing efficiencies. [Molecular Therapy-Nucleic Acids] AbstractFull Article