House Dust Mite-Induced Akt-ERK1/2-C/Ebp Beta Pathway Triggers CCL20-Mediated Inflammation and Epithelial–Mesenchymal Transition for Airway Remodeling

To investigate the role of C–C chemokine ligand 20 (CCL20) in chronic airway inflammation and remodeling, researchers made a mouse model of CCL20-induced bronchial asthma.