ESE3-Positive PSCs Drive Pancreatic Cancer Fibrosis, Chemoresistance and Poor Prognosis via Tumor–Stromal IL-1β/NF–κB/ESE3 Signaling Axis

Scientists reported that epithelium-specific E-twenty six factor 3 (ESE3) expression increased in pancreatic stellate cells (PSCs) in PDAC tissues compared with those in normal PSCs.