NewslettersImmunology of Infectious Disease News Comparison of Replicating and Nonreplicating Vaccines against SARS-CoV-2 By Danielle Corrigan - August 25, 2022 0 Researchers tested the utility of replication in a vaccine by comparing replication-defective adenovirus and replicating single-cycle adenovirus vaccines that expressed the SARS-CoV-2 spike protein. [Science Advances] Full Article