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MAB21L4 Deficiency Drives Squamous Cell Carcinoma via Activation of RET

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Investigators performed a transcriptome-wide screen for genes of unknown function that possess inverse expression patterns in differentiating keratinocytes compared with cutaneous squamous cell carcinomas, leading to the identification of MAB21L4 as an enforcer of terminal differentiation that suppresses carcinogenesis.
[Cancer Research]
Abstract
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