Acquisition and Maintenance of Pluripotency Are Influenced by Fibroblast Growth Factor, Leukemia Inhibitory Factor, and 2i in Bovine-Induced Pluripotent Stem Cells

Investigators reprogrammed fetal fibroblasts by transient expression of the four transcription factors and cultured in iPSC medium, and then compared these bovine iPSC lines with bovine ESC to evaluate the pluripotent state.