NewslettersImmune Regulation News A Specialized Tyrosine-Based Endocytosis Signal in MR1 Controls Antigen Presentation to MAIT Cells By lbeveridge - September 23, 2022 0 The authors reported that human MR1 was equipped with a tyrosine-based motif in its cytoplasmic domain that mediates low affinity binding with the endocytic adaptor protein 2 complex. [Journal of Cell Biology] Abstract