NewslettersDermal Cell News Targeting the USP7/RRM2 Axis Drives Senescence and Sensitizes Melanoma Cells to Hdac/LSD1 Inhibitors By Bob - September 26, 2022 0 Researchers show that USP7 downregulation induced cellular senescence, arresting melanoma growth in vivo and proliferation in vitro in BRAF- and NRAS-mutant melanoma. [Cell Reports] AbstractFull ArticleGraphical Abstract