NewslettersESC & iPSC News Exploration of Nuclear Body-Enhanced Sumoylation Reveals That PML Represses 2-Cell Features of Embryonic Stem Cells By lbeveridge - October 5, 2022 0 The authors demonstrated that PML was essential for oxidative stress-driven partner SUMO2/3 conjugation in mESCs or leukemia, a process often followed by their poly-ubiquitination and degradation. [Nature Communications] Full ArticleGraphical Abstract