NewslettersPulmonary Cell News Afatinib Triggers a Ni2+-Resistant Ca2+ Influx Pathway in A549 Non-Small Cell Lung Cancer Cells By Jamie Kang - October 5, 2022 0 Investigators examined if afatinib had cytotoxic action against NSCLC other than inhibition of tyrosine kinase and discovered that afatinib caused apoptotic death in a concentration-dependent manner. [Fundamental & Clinical Pharmacology] Abstract