Home Newsletters Cancer Stem Cell News Aberrant Phosphorylation Inactivates Numb in Breast Cancer Causing Expansion of the Stem...

Aberrant Phosphorylation Inactivates Numb in Breast Cancer Causing Expansion of the Stem Cell Pool

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Researchers showed that asymmetric Numb partitioning per se is insufficient for the proper control of mammary stem cell dynamics, with differential phosphorylation and functional inactivation of Numb in the two progeny also required.
[Journal of Cell Biology]
Abstract
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