NewslettersHuman Immunology NewsImmune Regulation News Colorectal Cancer Metastases in the Liver Establish Immunosuppressive Spatial Networking between Tumor Associated SPP1+ Macrophages and Fibroblasts By lbeveridge - October 17, 2022 0 Scientists identified tumor microenvironment-specific SPP1-expressing macrophages with altered metabolism features, foam cell characteristics and increased activity in extracellular matrix organization. [Clinical Cancer Research] Abstract