NewslettersExtracellular Matrix NewsOrganoid News Extracellular Matrix Drives Tumor Organoids toward Desmoplastic Matrix Deposition and Mesenchymal Transition By Bob - December 1, 2022 0 The authors combined cholangiocarcinoma organoids with native tumor and liver scaffolds, obtained by decellularization, to effectuate a model to study the interaction between epithelial tumor cells and their surrounding ECM. [Acta Biomaterialia] Abstract