NewslettersDermal Cell News BRD4 Inhibitor Suppresses Melanoma Metastasis via the SPINK6/EGFR-EphA2 Pathway By Laurisa Dohm - December 12, 2022 0 Findings indicated that BET inhibition suppressed melanoma metastasis both in vitro and in vivo, and identified a new mechanism by which BET inhibitors bloked the direct interaction of BRD4 and the SPINK6 enhancer. [Pharmacological Research] Full Article