Scientists showed that KLF4 upregulation accompanied vascular smooth muscle cells’ phenotypic switching in atherosclerotic lesions. KLF4 enhanced the metabolic switch to glycolysis by increasing PFKFB3 expression.
[Communications Biology]
Home Newsletters Muscle Cell News KLF4-PFKFB3-Driven Glycolysis Is Essential for Phenotypic Switching of Vascular Smooth Muscle Cells
