NewslettersMammary Cell NewsProstate Cell News PRSS2 Remodels the Tumor Microenvironment via Repression of Tsp1 to Stimulate Tumor Growth and Progression By Noshin Noorjahan - January 6, 2023 0 Scientists identified a novel tumor-mediated mechanism that repressed the expression of thrombospondin-1 (Tsp-1) in the tumor microenvironment via secretion of the serine protease PRSS2. [Nature Communications] Full Article